Desmond Miles (1987 – 2012) was a member of the
Assassin Order and a descendant of numerous familial lines that had sworn an allegiance to the Assassins; including individuals such as
Aquilus,
Altaïr Ibn-La'Ahad,
Ezio Auditore da Firenze,
Edward Kenway, and
Ratonhnhaké:ton.
By age 16, Desmond became tired of living in hiding and aspired to pursue his own dreams. Using the minimal training of Assassin skills he had obtained from his father,
William Miles, Desmond fled from the Assassin compound he had grown up in and managed to travel from
South Dakota to
New York City, where he found employment as a bartender in the
Bad Weather nightclub.
In September 2012, Desmond was kidnapped and incarcerated by
Abstergo Industries, a
Templar organization, and forced into a machine called the
Animus to relive the
genetic memories of his ancestor, Altaïr Ibn-La'Ahad. It was Abstergo's aim to acquire a map that detailed many "
Pieces of Eden" spread across the Earth, which Desmond was reluctantly successful in doing. Following this, he managed to escape Abstergo with the help of
Lucy Stillman, an undercover Assassin, and joined an Assassin cell in
Italy, which consisted of herself,
Shaun Hastings and
Rebecca Crane. Utilizing an upgraded Animus of Rebecca's construction, Desmond relived the memories of Ezio Auditore da Firenze, in order to improve upon his newly obtained skills.
Eventually, with the knowledge gained from Ezio's memories, Desmond and his fellow Assassins obtained the location of
Ezio's Apple of Eden, which was located underneath the
Colosseum. Though successful in obtaining the artifact, Desmond's body was taken over by
Juno, a member of the
First Civilization, and was made to stab Lucy after Juno revealed her to be a traitor. As a result of the shock, Desmond fell into a coma, and was placed in the
Black Room, the safe mode of the Animus, in an attempt to stabilize his condition. With help from the virtual construct of
Clay Kaczmarek, "Subject 16" of Abstergo's
Animus Project, Desmond was able to regain consciousness, and found himself located in the state of New York once more, this time with Rebecca, Shaun, and his father, William.
While in the Grand Temple, Desmond relived the memories of
Haytham Kenway and Ratonhnhaké:ton to find the
key to the sanctum containing the
device needed to prevent a
devastating solar wind. He also undertook field missions to retrieve power sources for the Temple, coming into conflict with
Daniel Cross. After his father was captured, Desmond rescued him from Abstergo's
Roman facility, and assassinated Cross and
Warren Vidic in the process.
After finding the key, Desmond opened the sanctum, but discovered he had been misled. It was made known that the device would save the world, but also unleash Juno, who had been imprisoned because of her hatred for humanity; using the device would also claim Desmond's life. Regardless, Desmond chose to sacrifice himself for humanity's survival, while expressing faith that his fellow Assassins would find a way to stop the new threat.
MGIV and aftermath
Desmond is rare in the multiverse. He was chosen for a Murder Game by the mysterious shadowed man. He died in the game, and didn't come back to life like the others. When he finally did come back it was an odd pocket universe that was almost immediately erased alongside its occupants. Its more than likely that Desmond is not actually the same Desmond that was in MGIV, but rather a copy like most of the others there, one that managed to escape with his new life instead of being erased with the others.
In the intermission Desmond has been traveling the universe, hunting for a mysterious man that the shadowed man sent him after in between gathering allies for his new Order.
Together with John Crichton and River Tam, the three of them created something of an ad hoc Assassin's Order to hunt for the mysterious man and help against the Akibahara threat. They don't have many members, and have been mainly focused on hunting for that mysterious man.